-LRB- CNN -RRB- -- Defending champion Rafael Nadal cruised into the third round of the clay-court Rome Masters event with a 6-1 6-3 victory over Philipp Kohlshreiber .

The world number three , seeking his fifth title in six years in the Italian capital , made just 11 unforced errors , compared to 28 by the German .

Nadal , 23 , broke his opponent 's serve twice in a one-sided first set .

The German world number 29 improved in the second set and missed a chance to take a 3-2 lead when he wasted his only break point of the match .

Nadal , who has only ever lost once at the Rome Masters , broke in the next game and pressed on to take the match .

Elsewhere , fifth seed Robin Soderling of Sweden beat Italian wild card Paolo Lorenzi 6-1 7-5 to reach the third round .

The Swede smashed 32 winners as he wrapped up victory in less than one and a quarter hours .

Guillermo Garcia-Lopez of Spain also progressed with a 6-2 6-3 win over former Wimbledon and U.S. Open champion Lleyton Hewitt .

Second seed Novak Djokovic and fourth seed Andy Murray both reached the third round on Tuesday while world number one Roger Federer crashed out to Latvian Ernests Gulbis .

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Rafael Nadal beats Philipp Kohlshreiber to reach third round of Rome Masters .

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The Spaniard wins 6-1 6-3 to stay on course for fifth Rome title in sixth years .

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Robin Soderling and Guillermo Garcia-Lopez also reach third round .